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EVE-PMS Diagnostic Skin Test Panel and Solvent
- Development stage
- Unknown
- Lead developer
- EVE Medical Systems
- Modality
- Small Molecules
- Administration
- Intradermal
01
Overview
The EVE-PMS Diagnostic Skin Test Panel and Solvent is a diagnostic and control component of the EVE-PMS technology developed by EVE Medical Systems Ltd. for the management of severe premenstrual syndrome (PMS). The diagnostic panel consists of four sex hormones—progesterone, estradiol, estrone, and estriol—dissolved in a solvent of ethyl oleate and 10% benzyl alcohol. It is utilized to identify specific hormone hypersensitivities in women by observing skin reactions following intradermal administration during the luteal phase of the menstrual cycle. In the specific 'Skin test panel and solvent' protocol, the diagnostic testing is followed by a control treatment phase where patients receive intradermal injections of the solvent alone (ethyl oleate and benzyl alcohol) in increasing volumes, rather than the active hormone desensitization kit. This system is designed to evaluate the efficacy of hormone desensitization therapy against a negative control in reducing or eliminating PMS symptoms associated with sex hormone hypersensitivity.
- Brand names
- EVE-PMS
- Other names
- Skin test panel and solventDiagnostic Skin Test PanelEVE-PMS technology
02
Targets
ER (Estrogen receptor)PR (Progesterone receptor)
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