Drug intelligence / Profile preview

Evernia prunastri

Development stage
Preclinical
Modality
Small Molecules
Administration
Topical, Oral, Inhalation, Intradermal
01

Overview

*Evernia prunastri*, commonly known as oakmoss, is a fruticose epiphytic lichen species widely distributed in the Northern Hemisphere. It is traditionally utilized in the perfume industry and as a spice in various cultures. Beyond its commercial uses, *Evernia prunastri* is extensively studied for its rich profile of bioactive secondary metabolites, including evernic acid, atranorin, usnic acid, and atraric acid. These compounds exhibit a broad spectrum of pharmacological activities, including antimicrobial, antioxidant, anti-inflammatory, and anticancer properties. Research has demonstrated its potential in sensitizing glioblastoma cells to temozolomide by modulating the Wnt signaling pathway and inhibiting enzymes such as acetylcholinesterase and tyrosinase, suggesting potential applications in neurodegenerative diseases like Alzheimer's and Parkinson's. Additionally, the lichen is employed as a sensitive biomonitor for environmental pollutants, including heavy metals, pesticides, and microplastics.

Other names
Evernia prunastri (L.) Ach.Oakmoss
02

Targets

AcetylcholinesteraseSucrase-IsomaltaseButyrylcholinesterasePTGS2 (Prostaglandin-Endoperoxide Synthase 2)TYR (Tyrosinase)

Beyond the preview

Go deeper on Evernia prunastri.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Evernia prunastri.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call