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**EVM-101** is Enveric Biosciences' first-generation oral psilocybin drug candidate that was being developed with the University of Calgary's Hotchkiss Brain Institute for **Cancer Related Distress** in oncology patients. Publicly available sources describe it as a **psilocybin-based psychedelic small-molecule therapy**, intended to improve core symptoms of cancer-related psychological distress such as anxiety, depressed mood, demoralization, and stress-associated manifestations. Enveric later stated that the original EVM101 classic psilocybin program had been **discontinued** as the company prioritized newer psilocybin-derived programs.
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