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ex vivo expanded umbilical cord blood

Development stage: Phase 2
Lead developer: Gamida Cell
Modality: Stem Cell Therapies → Cell Therapies
Administration: Intravenous

Overview

Ex vivo expanded umbilical cord blood is an investigational **allogeneic hematopoietic stem and progenitor cell therapy** developed by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins for transplantation after myeloablative conditioning in hematologic malignancies. The treatment consists of cord blood-derived hematopoietic cells expanded outside the body to increase the available progenitor-cell dose and support more rapid early hematopoietic recovery, particularly neutrophil engraftment. In the registered Phase 1/2 protocol, the expanded cord blood product was co-infused with a separate unexpanded cord blood unit intended to provide durable long-term engraftment. ([patlynk.com](https://www.patlynk.com/trial/NCT00539656))

Other names: ex vivo expanded umbilical cord blood cellsexpanded umbilical cord blood

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