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EX042-002-06

Development stage: Preclinical
Lead developer: Excelsior Biopharma
Modality: Small Molecules
Administration: Parenteral

Overview

EX042-002-06 is an early-stage small molecule inhibitor currently in preclinical development by Excelsior Biopharma. The therapeutic candidate targets the transforming growth factor-beta (TGF-β) receptor to modulate or inhibit its downstream signaling pathways. Aberrant TGF-β signaling is a well-known driver of immune evasion, epithelial-to-mesenchymal transition (EMT), and metastasis within the tumor microenvironment. Excelsior Biopharma is exploring the development of EX042-002-06 for the treatment of rare cancers.

Targets

TGFBR (TGF-beta receptor)

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