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exenatide implant
- Development stage
- Phase 2
- Lead developer
- Vivani Medical, Inc
- Modality
- Peptides, Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
- Administration
- Implant
01
Overview
Exenatide implant is a long-acting drug-device combination that delivers the glucagon-like peptide-1 (GLP-1) receptor agonist exenatide via a miniature subdermal medical implant. It is designed to provide sustained release of exenatide for up to six months, aiming to improve glycemic control in adults with type 2 diabetes mellitus and support weight loss in obesity. The mechanism of action involves GLP-1 receptor agonism, which stimulates glucose-dependent insulin secretion, suppresses glucagon secretion, slows gastric emptying, and reduces food intake. The technology seeks to address medication non-adherence and tolerability issues associated with oral or injectable formulations by offering consistent therapeutic delivery over an extended period[2][3][6].
- Other names
- exenatide implantNPM 119NPM119NPM-119NPM 115NPM115NPM-115
02
Targets
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