Drug intelligence / Profile preview

Exosirylic

Development stage
Unknown
Lead developer
Gypto Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Exosirylic is an oral film-coated tablet containing ursodeoxycholic acid (UDCA), a naturally occurring bile acid used for the treatment of cholesterol-related gallbladder and liver conditions. Manufactured by Gypto Pharma, it is primarily indicated for the dissolution of radiolucent, non-calcified cholesterol gallstones (not exceeding 15 mm in diameter) in patients with a functioning gallbladder. Ursodeoxycholic acid works by suppressing the hepatic synthesis and secretion of cholesterol and by inhibiting its intestinal absorption. This process leads to the desaturation of bile with cholesterol, facilitating the gradual dissolution of cholesterol gallstones. Additionally, UDCA is utilized in the management of primary biliary cholangitis and other cholestatic liver diseases due to its cytoprotective and choleretic effects.

Brand names
Exosirylic
Other names
Exosirylic 500 mg Film Coated TabletsExosirylic500 mg Film Coated TabletsExosirylic-500 mg Film Coated TabletsExosirylic 250 mg Film Coated TabletsExosirylic250 mg Film Coated TabletsExosirylic-250 mg Film Coated Tablets
02

Targets

GPBAR1HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)FXR (Farnesoid x-activated receptor)

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