Drug intelligence / Profile preview

EXP018

Development stage
Preclinical
Lead developer
Excalipoint Therapeutics
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

EXP018 is a masked or probody T-cell engager (Pro-TCE) in development by Excalipoint Therapeutics for the treatment of solid tumors. Developed using the company's proprietary EXPROMA™ (TCE Probody) platform, EXP018 is designed to conditionally engage T cells within the tumor microenvironment, thereby minimizing systemic toxicity and off-target effects. The specific tumor-associated antigen targeted by EXP018 remains undisclosed.

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