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Experimental Dentifrice 2

Development stage: Preclinical
Lead developer: HALEON
Modality: Small Molecules
Administration: Topical

Overview

**Experimental Dentifrice 2** is an investigational Haleon potassium nitrate dentifrice evaluated for removal of extrinsic dental stain. The formulation designated ED2 contained 5% sodium tripolyphosphate and 1% micronized alumina with abrasive silica, in addition to potassium nitrate, and was designed to provide daily-use stain removal and tooth-shade improvement while retaining an anti-dentin-hypersensitivity dentifrice profile. In an 8-week randomized, controlled clinical study, ED2 was compared with a regular fluoride dentifrice in participants with extrinsic dental stain. ([onlinelibrary.wiley.com](https://onlinelibrary.wiley.com/doi/epdf/10.1111/jerd.13373))

Other names: ED2ED-2ED 2

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