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Patch 2 refers to an **expired allergen series** used as a diagnostic intervention in clinical research conducted by the University of Calgary. It is specifically utilized in a Phase 4 comparative study (NCT05046470) to evaluate the reliability and reactivity of allergens that have passed their manufacturer-provided expiration dates compared to non-expired series (Patch 1). The primary indication for this diagnostic tool is the identification of triggers for **allergic contact dermatitis**. Patch testing works by inducing a delayed-type hypersensitivity reaction (Type IV) in sensitized individuals. This study aims to determine if expired products maintain sufficient stability and diagnostic accuracy, which could lead to significant cost-savings and improved accessibility for dermatology practices that often have expired allergens accessible but do not routinely use them.
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