Drug intelligence / Profile preview

Eyestil Plus

Development stage
Unknown
Lead developer
SIFI
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Eyestil Plus is a preservative-free ophthalmic solution developed by SIFI for the management of moderate-to-severe dry eye syndrome. It is a combination product containing 0.4% sodium hyaluronate and 0.5% taurine. Sodium hyaluronate, a high-molecular-weight glycosaminoglycan, provides viscoelastic and mucoadhesive properties that stabilize the tear film and lubricate the ocular surface. Taurine acts as an osmoprotectant, helping corneal epithelial cells maintain volume and integrity under hyperosmotic conditions typical of dry eye, and provides antioxidant protection against oxidative stress. The formulation is designed to provide long-lasting relief from symptoms such as burning and foreign body sensation while promoting the repair of the corneal epithelium.

Brand names
Eyestil Plus
Other names
Eyestil Plus ophthalmic solutionEyestil Plus 0.4%
02

Targets

CD44 (CD44 antigen)SLC6A6 (Solute carrier family 6 member 6)

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