Drug intelligence / Profile preview

FabenFLU

Development stage
Phase 1
Lead developer
Fabentech
Modality
Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

**FabenFLU** is a polyclonal antibody fragment (F(ab')2) immunotherapy developed by Fabentech for post-exposure treatment of H5N1 avian influenza infection, a highly pathogenic virus with up to 60% human mortality and no approved treatments available. Produced using the proprietary FabShield® platform, it neutralizes over 20 H5N1 viral strains by binding multiple epitopes, offering broad protection against variants with improved tissue penetration and low immunogenicity compared to whole antibodies. It has completed development, achieved Phase I clinical safety validation, and received EU Orphan Drug Designation, positioning it as a stockpiled medical countermeasure for potential pandemics.

Brand names
FabenFLU
Other names
FabenfluFabenflu®anti-H5N1 immunoglobulinanti-H-5N1 immunoglobulinanti-H 5N1 immunoglobulin
02

Targets

HA (Hemagglutinin)

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