Drug intelligence / Profile preview

FagolitosPlus

Development stage
Unknown
Lead developer
Arafarma
Modality
Small Molecules
Administration
Oral
01

Overview

FagolitosPlus is a food supplement developed and manufactured by Arafarma Group for the prevention and treatment of renal lithiasis, specifically calcium oxalate and calcium phosphate kidney stones. It is administered orally as sustained-release granules in sachets, designed to release its components over a 24-hour period. The product contains a combination of hydroxycitric acid (HCA) derived from *Garcinia cambogia* extract, magnesium, vitamin B6, zinc, and vitamin A. Its mechanism of action involves hydroxycitric acid inhibiting the crystallization and promoting the dissolution of calcium-based stones through electrostatic interactions with calcium ions. Additionally, magnesium helps reduce the intestinal absorption of dietary oxalate, while vitamin B6 aids in reducing the endogenous production of oxalate. Clinical trials have evaluated FagolitosPlus as an adjuvant to extracorporeal shock wave lithotripsy (ESWL), demonstrating improved stone fragmentation rates compared to placebo.

Brand names
FagolitosPlusFagolitos Plus
02

Targets

CaCO3 (Calcium carbonate)

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