Drug intelligence / Profile preview

Fagus grandifolia pollen extract

Development stage
Approved
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Intradermal, Subcutaneous, Sublingual, Intranasal, Inhalation, Ophthalmic
01

Overview

Fagus grandifolia pollen is an allergenic extract derived from the pollen of the Fagus grandifolia plant, also known as the American beech tree. [12] It is a biologic product approved under a Biologic License Application and has been marketed since 1941. This extract is used for both diagnosing and treating immediate hypersensitivity allergies to beech tree pollen. [1, 3] As a diagnostic tool, it is applied via skin tests to confirm sensitivity. [1, 3, 5] For therapeutic purposes, it is used in allergen immunotherapy, where repeated and gradually increasing doses are administered to desensitize the immune system. [1, 3] This desensitization process works by modulating the body's immune response to the pollen, particularly by shifting away from an IgE-mediated allergic reaction towards a state of tolerance. [1, 14]

Brand names
Beech PollenCENTER-AL
Other names
Fagus grandifolia pollenAmerican beech tree pollen extractAmerican Beech Pollen
02

Targets

IgE (Immunoglobulin E)

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