Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
FAK-FAT stapled peptide
- Development stage
- Preclinical
- Lead developer
- FAKnostics
- Modality
- Peptides
01
Overview
FAKnostics is developing a hydrocarbon-stapled peptide that specifically targets the Focal Adhesion Targeting (FAT) domain of Focal Adhesion Kinase (FAK, also known as PTK2). Unlike traditional small-molecule FAK inhibitors that target the ATP-binding kinase domain, this peptide is designed to disrupt the non-kinase scaffolding functions of FAK. By interfering with the protein-protein interactions mediated by the FAT domain (such as those with paxillin and VEGFR3), the drug aims to inhibit tumor cell survival, migration, and the development of the dense, fibrotic stroma characteristic of pancreatic ductal adenocarcinoma (PDAC). The program is currently in the IND-enabling phase of development.
- Other names
- FAKnostics FAK-FAT stapled peptideFAK FAT domain-hydrocarbon-stapled peptideFAKnostics Therapeutics - Pancreatic CancerFAKnostics-FAK FAT domain-hydrocarbon-stapled peptide-pancreatic cancer
02
Targets
FAK (Focal adhesion kinase)
Beyond the preview
Go deeper on FAK-FAT stapled peptide.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on FAK-FAT stapled peptide.