falintolol

Falintolol is a **small molecule drug** that acts as a **beta-adrenergic receptor antagonist** (beta-blocker), specifically targeting β-adrenoceptors[2]. It has been primarily investigated for the **reduction of intraocular pressure (IOP)** in the treatment of **open-angle glaucoma** and other eye diseases[2]. Preclinical studies have shown that topical falintolol reduces IOP similarly to timolol but with a longer duration of action and faster corneal transport[2]. Unlike other beta-blockers, falintolol has demonstrated minimal systemic side effects upon ocular use[2]. Its mechanism involves blocking β-adrenoceptors, thereby inhibiting sympathetic stimulation in ocular tissues, which lowers IOP. The drug has also been studied for tissue distribution and elimination, showing significant ocular tissue penetration after topical administration and elimination primarily via urinary excretion[2].

Brand names

falintolol

Other names

falintololfalintolol maleate