famtozinameran

Famtozinameran is a nucleoside-modified messenger RNA (mRNA) component of the bivalent COVID-19 vaccine Comirnaty Original/Omicron BA.4-5, which also contains tozinameran. Famtozinameran encodes the spike protein of SARS-CoV-2 Omicron variant lineages BA.4 and BA.5, enabling host cells to transiently express this antigen after intramuscular injection. The mRNA is delivered via lipid nanoparticles, leading to an immune response that includes both neutralizing antibodies and cellular immunity against COVID-19[1][3][6]. This vaccine is primarily used as a booster for individuals 12 years and older to prevent COVID-19[7]. It was developed by BioNTech in collaboration with Pfizer.