fanft

FANFT is a **synthetic nitrofuran derivative** with the chemical name **N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide** and molecular formula C8H5N3O4S[7]. It is a **dark yellow powder or gold solid** and is **insoluble in water**[2]. FANFT is primarily used as a research chemical and is recognized as a **potent urinary bladder carcinogen** in animal studies[8][2][6]. Its carcinogenic and mutagenic effects serve as a model for studying chemical carcinogenesis, particularly related to nitrofuran derivatives, affecting organs such as the bladder, forestomach, mammary gland, and kidney[2][8]. Its mechanism of toxicity involves metabolic activation likely associated with the nitro group on the furan ring. FANFT has demonstrated mutagenic and reproductive toxicity in experimental systems[2]. It is not intended for human or veterinary use[2].

Other names

N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamideN-[4-(5-Nitro-2-furyl)-2-thiazolyl]formamide2-Formylamino-4-(5-nitro-2-furyl)thiazole