Drug intelligence / Profile preview

fangji huangqi

Development stage
Unknown
Lead developer
Cui Xuejun
Administration
Oral
01

Overview

Fangji Huangqi is a traditional Chinese medicine (TCM) formula, also known in Japanese Kampo medicine as Boiogito. It typically consists of six herbal ingredients: *Stephania tetrandra* (Fangji), *Astragalus membranaceus* (Huangqi), *Atractylodes macrocephala* (Baizhu), *Glycyrrhiza uralensis* (Gancao), *Zingiber officinale* (Shengjiang), and *Ziziphus jujuba* (Dazao). Historically used to treat conditions characterized by "wind-dampness" and edema, it is currently being investigated for its efficacy in managing active knee osteoarthritis (KOA). The formula is thought to provide analgesic and anti-inflammatory effects by reducing joint swelling and potentially protecting against cartilage degeneration. In clinical research, it has been studied both as a monotherapy and in combination with non-steroidal anti-inflammatory drugs (NSAIDs) like meloxicam (Mobic) to improve physical function and reduce pain in patients with degenerative joint diseases.

Brand names
Fangji Huangqi Pill
Other names
boiogitoFangji Huangqi TangFangji Huangqi WanBoi-ogi-to
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)IL1B (Interleukin-1 beta)TNFA (Tumor necrosis factor alpha (soluble))

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