Drug intelligence / Profile preview

Fantom Encore

Development stage
Unknown
Lead developer
REVA Medical
Modality
Small Molecules, Device-based Delivery → Drug Delivery Systems
Administration
Percutaneous
01

Overview

Fantom Encore is a third-generation sirolimus-eluting bioresorbable scaffold (BRS) developed by REVA Medical for the treatment of coronary artery disease. It is constructed from Tyrocore, a proprietary, radiopaque, tyrosine-derived polymer that allows for full visibility under X-ray without the need for platinum markers. The device features thin struts (95-115 μm) and is designed to provide temporary mechanical support to the coronary artery during the healing process before being fully resorbed by the body over a period of 36 to 48 months. The scaffold elutes sirolimus, an antiproliferative agent, to prevent neointimal hyperplasia and restenosis. It received CE Mark approval in 2018 as an alternative to permanent metallic drug-eluting stents.

Brand names
Fantom Encore
Other names
Fantom Encore BRSFantom Encore Sirolimus-Eluting Bioresorbable Scaffold
02

Targets

Mechanistic target of rapamycin complex 1

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