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Farnesyl thiopyrophosphate

Development stage
Unknown
Modality
Small Molecules
01

Overview

Farnesyl thiopyrophosphate (FsPP) is a synthetic analog of farnesyl pyrophosphate (FPP). It acts as an inhibitor of undecaprenyl pyrophosphate synthase (UPPs), an enzyme involved in the synthesis of undecaprenyl pyrophosphate, a lipid carrier essential for bacterial cell wall formation. FsPP has been extensively used in biochemical research to study the kinetics, inhibition, and conformational changes of UPPs, serving as a valuable tool for understanding this enzyme's function and for identifying potential drug targets.

Other names
(S)-Farnesyl thiopyrophosphate
02

Targets

UppS (Undecaprenyl diphosphate synthase)

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