Drug intelligence / Profile preview

fascin inhibitor

Development stage
Unknown
Lead developer
Protheragen
Modality
Small Molecules
Administration
Intraperitoneal
01

Overview

Fascin inhibitors are a class of small molecule therapeutics designed to target and inhibit the actin-bundling protein fascin, specifically the fascin-1 isoform. Fascin-1 is frequently overexpressed in various metastatic cancers and is essential for the formation of filopodia, which are cellular protrusions that facilitate tumor cell migration and invasion. By blocking the actin-bundling activity of fascin, these inhibitors aim to reduce the metastatic potential of cancer cells and improve patient outcomes. Protheragen is developing a fascin inhibitor as a small molecule therapeutic for the treatment of cancer, which is currently in Phase I clinical development.

Other names
fascin inhibitorfascin-1 inhibitorfascin1 inhibitorfascin 1 inhibitor
02

Targets

FSCN1

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