Drug intelligence / Profile preview

fazadinium bromide

Development stage
Unknown
Modality
Small Molecules
Administration
Intravenous
01

Overview

Fazadinium bromide is a non-depolarizing neuromuscular blocking agent used as a muscle relaxant in anesthesia. It acts as an antagonist at the nicotinic acetylcholine receptor at the neuromuscular junction, producing muscle relaxation by inhibiting synaptic transmission. The drug has a rapid onset and intermediate duration of action. It was marketed under the trade name Fazadon and is classified as a quaternary ammonium compound type muscle relaxant[1][6][7]. Its primary indication was to facilitate endotracheal intubation and provide skeletal muscle relaxation during surgery or mechanical ventilation[6]. The current marketing status is unknown.

Brand names
Fazadon
Other names
fazadinium bromideFazadonBromuro de fazadinioBromure de fazadiniumFazadinii bromidumFAZADINIUM BROMIDE (MART.)Imidazo(1,2-a)pyridinium, 1,1'-azobis(3-methyl-2-phenyl-, dibromideFazadinium dibromide
02

Targets

Muscle-type nicotinic acetylcholine receptor

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