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FD2056
- Development stage
- Preclinical
- Lead developer
- Fudan University
01
Overview
FD2056: sourced facts only. name: "Among them, compound FD2056 stands out as the most promising candidate, maintaining potent inhibitory activity against PI3K and enhanced CDK2 inhibition, and showing moderate selectivity among 108 kinases." [PMID:37579621]; target: "Among them, compound FD2056 stands out as the most promising candidate, maintaining potent inhibitory activity against PI3K and enhanced CDK2 inhibition, and showing moderate selectivity among 108 kinases." [PMID:37579621]; developer: "Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China." [PMID:37579621]; stage: "Moreover, FD2056 showed more efficacious anti-TNBC activity than the corresponding drugs BKM120 and CYC202 at an oral dose of 15 mg/kg in the MDA-MB-231 xenograft model, inhibiting tumor growth by 43% with no observable toxic effects." [PMID:37579621]
02
Targets
CDK2 (Cyclin-dependent kinase 2)
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