Drug intelligence / Profile preview

FEC with docosahexaenoic acid

Development stage
Preclinical
Lead developer
Takeda
Modality
Small Molecules
Administration
Intravenous, Oral
01

Overview

This appears to be a modified version of the standard FEC (Fluorouracil, Epirubicin, Cyclophosphamide) chemotherapy regimen with the addition of docosahexaenoic acid. The standard FEC combination is commonly used in the treatment of breast cancer. In this regimen, fluorouracil acts as a pyrimidine antagonist, epirubicin is an anthracycline that inhibits DNA and RNA synthesis, and cyclophosphamide is an alkylating agent. The addition of docosahexaenoic acid to this combination is not documented in the provided search results, suggesting this may be an experimental or investigational modification of the standard regimen.

Other names
CEF with docosahexaenoic acid
02

Targets

FFAR4 (Free fatty acid receptor 4)TS (Thymidylate synthase)DPYD (Dihydropyrimidine dehydrogenase)DNA

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