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fecal microbiota transplant (Lifespan Biotech)
- Development stage
- Unknown
- Lead developer
- Lifespan
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral, Rectal, Intranasal
01
Overview
Fecal microbiota transplant (FMT) from Lifespan Biotech is an investigational live biotherapeutic product for the treatment of nonalcoholic steatohepatitis (NASH). The therapy involves transferring fecal matter from healthy, lean donors to patients with NASH with the goal of restoring a healthy gut microbiome. The underlying hypothesis is that correcting the imbalance of gut bacteria (dysbiosis), which is suspected to be a key driver in the progression of fatty liver disease, can be beneficial. A pilot study was initiated to evaluate the safety and efficacy of this approach.
- Other names
- FMT in NASHfecal microbiota transplantation-Lifespan-nonalcoholic steatohepatitis
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