Drug intelligence / Profile preview

fecal microbiota transplant capsules

Development stage: Unknown
Lead developer: Vrije University Medical Center
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

Fecal microbiota transplant (FMT) capsules, specifically the lyophilised fecal microbiota capsules (LFMCs) developed by Amsterdam UMC, are an investigational microbiome-based therapeutic. These oral capsules contain freeze-dried fecal microbiota obtained from healthy vegan donors. The therapy is designed to modulate the gut microbiome to address the gut-liver axis, aiming to reduce hepatic necroinflammation and steatohepatitis. In clinical studies (notably NCT05821010), they are being evaluated for the treatment of non-alcoholic steatohepatitis (NASH) and metabolic dysfunction-associated steatohepatitis (MASH), typically administered in conjunction with a synbiotic cocktail consisting of *Anaerobutyricum soehngenii*, pasteurized *Akkermansia muciniphila*, *Bifidobacterium animalis* subsp. *lactis*, and fructo-oligosaccharides.

Other names: lyophilised fecal microbiota capsulesconditioned fecal microbiota transplantation capsules

Beyond the preview

Go deeper on fecal microbiota transplant capsules.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on fecal microbiota transplant capsules.

Explore the full profile