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fecal microbiota transplantation (4da768)
- Development stage
- Unknown
- Lead developer
- O.O. Bogomolets National Medical University
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Cell Therapies, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Rectal
01
Overview
Fecal microbiota transplantation (FMT) is an investigational biological therapy being studied by Bogomolets National Medical University for the treatment of mild-to-moderate ulcerative colitis. The therapy involves transplanting fecal material from healthy donors into a patient's colon via colonoscopy, with the goal of restoring a healthy gut microbiota composition. The active component is the entire microbial community within the donor's fecal matter. [2] In the context of the NCT05538026 clinical trial, it was evaluated as an add-on therapy to a standard treatment regimen of mesalazine.
- Other names
- FMTfecal microbiota transplantfecal transplantation-Bogomolets National Medical University-ulcerative colitis
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