Drug intelligence / Profile preview

fecal microbiota transplantation-Assaf Harofeh MC

Development stage
Unknown
Lead developer
Shamir Medical Center
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Fecal microbiota transplantation (FMT) developed by Assaf Harofeh Medical Center (now Shamir Medical Center) is a microbial therapy involving the transfer of processed stool from healthy donors into a recipient. This specific preparation is administered via oral capsules. The primary objective of this FMT is to restore a diverse and functional gut microbiome following depletion or dysbiosis. In clinical research conducted by the institution, it is being investigated for its potential to modulate physical performance, metabolic parameters, and glycemic responses in humans, particularly after antibiotic-induced microbiome disruption.

Other names
FMTFecal Microbiota Transplantation

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