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Feel Free Tonic

Development stage: Unknown
Lead developer: Botanic Tonics
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Feel Free Tonic is a plant-based liquid botanical blend developed and marketed by Botanic Tonics, LLC. It is formulated as a dietary supplement containing noble kava root extract and ground natural leaf kratom, along with kola nut, rhodiola, and lion's mane. The tonic is designed for healthy adults to enhance mood, focus, and relaxation. Its mechanism of action involves kavalactones targeting GABA-A receptors to provide anxiolytic effects, and kratom alkaloids like mitragynine acting on opioid and adrenergic receptors to provide energy and mood support. The product has been evaluated in independent clinical trials for safety and efficacy in healthy adults.

Brand names: feel free CLASSIC
Other names: feel free

Targets

MOR (Mu opioid receptor)ADRA2A (α2A)GABRR (GABA-A receptor subunit rho)

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