Drug intelligence / Profile preview

FemSeven

Development stage
Unknown
Lead developer
Theramex
Modality
Small Molecules
Administration
Transdermal
01

Overview

FemSeven is a range of transdermal hormone replacement therapy (HRT) patches marketed by Theramex. The product line includes FemSeven (estradiol only), FemSeven Conti (estradiol and levonorgestrel), and FemSeven Sequi (estradiol and levonorgestrel in a sequential phase). Estradiol, a small molecule estrogen, works by supplementing declining hormone levels in menopausal women to alleviate symptoms such as hot flashes and night sweats. In the combination versions (Conti and Sequi), levonorgestrel is included as a progestogen to protect the lining of the womb (endometrium) from hyperplasia, which can be caused by unopposed estrogen. The patches are designed for once-weekly application, providing sustained release of the active ingredients through the skin.

Brand names
FemSevenFemSeven ContiFemSeven Sequi
Other names
estradiol transdermal patchestradiol + levonorgestrel transdermal patch
02

Targets

GPER1 (G protein-coupled estrogen receptor 1)ESR2 (ERβ)PR (Progesterone receptor)ESR1 (ERα)

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