Drug intelligence / Profile preview

Fenfuro

Development stage
Unknown
Lead developer
Chereso Lifesciences
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Fenfuro is a proprietary, patented formulation derived from the seeds of *Trigonella foenum-graecum* (fenugreek), standardized to contain a high concentration of furostanolic saponins. It is primarily used as a phytotherapeutic dietary supplement for the management of hyperglycemia and type 2 diabetes mellitus. Clinical studies have demonstrated that Fenfuro significantly reduces fasting and postprandial blood glucose levels as well as glycated hemoglobin (HbA1c) in diabetic patients when used alongside standard antidiabetic therapies such as metformin or sulfonylureas[2][7][8]. The mechanism of action involves improving insulin sensitivity, decreasing insulin resistance, delaying gastric emptying, inhibiting glucose transport by blocking lipid and carbohydrate-hydrolyzing enzymes, and increasing tissue responsiveness to insulin through upregulation of insulin receptor sites[6]. Fenfuro has shown a favorable safety profile with no significant adverse effects reported in clinical trials[2][7][8]. It may also be used for digestive disorders and menstrual pain relief due to its broad nutritional properties[4].

Brand names
FENFURO
Other names
fenugreek seed extractTrigonella foenum-graecum seed extractfurostanolic saponins from fenugreek
02

Targets

INSR (Insulin receptor)

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