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Fenoxazoline is a small molecule nasal decongestant used primarily for the relief of nasal congestion. It acts as a sympathomimetic agent by mimicking the effects of the sympathetic nervous system to constrict blood vessels in the nasal passages and reduce swelling. The drug is typically administered topically as a nasal solution. Its mechanism of action involves vasoconstriction through stimulation of alpha-adrenergic receptors in the nasal mucosa. Fenoxazoline has been marketed under various trade names including Aturgyl (in Brazil), Nasofelin, Nebulicina, Rhinox, Nasenol, and Nasostop. It has reached up to phase II clinical trials for at least one investigational indication.
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