fenpiverinium

Fenpiverinium is a small molecule anticholinergic and antispasmodic agent used primarily for the treatment of smooth muscle spasms and pain associated with gastrointestinal and urinary tract disorders[1][2][4]. It acts as a muscarinic acetylcholine receptor antagonist, inhibiting the action of acetylcholine at muscarinic receptors in smooth muscle. This leads to reduced contractions and motility in organs such as the gastrointestinal tract, providing symptomatic relief from spasms[4][5][6]. Fenpiverinium is often marketed in combination with other agents like pitofenone hydrochloride and either nimesulide or metamizole (notably under brand names such as Baralgin) in Eastern Europe and India[1][4]. The drug has been subject to regulatory changes due to safety concerns regarding its combinations. Its primary mechanism is exclusive antagonism at muscarinic acetylcholine receptors; it does not affect spontaneous phasic activity or activation by high potassium or norepinephrine[4].

Other names

fenpiverinium ionfenpiverinium cationfenpiverinium bromide