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Fentanyl WZF is a formulation of fentanyl citrate, a potent synthetic opioid analgesic, manufactured by WZF Polfa S.A. in Poland. It acts as a mu-opioid receptor agonist in the central nervous system, providing rapid-onset analgesia and sedation. In clinical practice, it is widely used for perioperative analgesia and the management of acute postoperative pain. In the context of research at the Medical University of Warsaw, Fentanyl WZF has been utilized as the standard-of-care opioid comparator in studies evaluating opioid-free anesthesia techniques for bariatric surgeries, such as laparoscopic sleeve gastrectomy. It is typically administered intravenously for the induction and maintenance of general anesthesia.
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