Drug intelligence / Profile preview

Fentin

Development stage
Unknown
Lead developer
Geofman Pharmaceuticals
Modality
Small Molecules
Administration
Intravenous, Intramuscular, Parenteral
01

Overview

Fentin is a brand name of phenytoin sodium injection (50 mg/mL) manufactured by Geofman Pharmaceuticals. Phenytoin is a well-established anticonvulsant (antiepileptic) drug used primarily for the control of generalized tonic-clonic (grand mal) and complex partial seizures, as well as for the prevention and treatment of seizures occurring during or following neurosurgery. In acute settings, such as status epilepticus, intravenous phenytoin is administered to rapidly stabilize neuronal membranes and suppress hyperexcitability. It acts by selectively blocking voltage-gated sodium channels in their inactive state, thereby inhibiting the sustained high-frequency repetitive firing of action potentials in the motor cortex.

Brand names
Fentin
Other names
Phenytoin sodium injection
02

Targets

SCN1A (Voltage-gated sodium channel protein type 1 subunit alpha)SCN2A (Voltage-gated sodium channel protein type 2 subunit alpha)SCN3A (Sodium channel protein type 3 subunit alpha)SCN5A (Sodium channel protein type 5 subunit alpha)SCN8A (NaV1.6)

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