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Fermented Papaya Preparation (FPP) is a sweet, granular substance made by the bio-fermentation of *Carica papaya*. It is available over-the-counter and is recognized for its potent antioxidant and anti-inflammatory properties. FPP is known to protect red blood cells against oxidative damage and has been investigated for its potential to improve diabetic wound healing by influencing wound-site macrophages and angiogenic responses. Additionally, it has been studied for its effects on cerebral energy metabolism, neuroinflammation, cognitive function, systemic inflammation, and iron status in patients with chronic kidney disease. FPP has a long history of safe human consumption.
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