Drug intelligence / Profile preview

fermented rice bran

Development stage
Preclinical
Lead developer
Ichimaru Pharcos
Administration
Oral
01

Overview

Fermented rice bran is a **microbially processed rice bran nutraceutical/dietary supplement** rather than a single defined pharmaceutical active ingredient. Across the cited literature, it is produced by fermenting rice bran with varying microbial consortia such as *Bacillus*, *Lactobacillus*, *Bifidobacterium*, *Aspergillus*, or yeast, which can increase bioavailable amino acids, gamma-aminobutyric acid, antioxidant metabolites, and vitamin B12 forms while reducing antinutritional factors and rancidity. Its reported biological effects are pleiotropic and formulation-dependent, with preclinical evidence for immunomodulatory, metabolic, gut-barrier, antioxidant, and antiviral benefits; however, there is no single validated molecular target or standardized drug product that applies across all fermented rice bran preparations. In the provided human trial context, fermented rice bran appears as a **component** of the hangover supplement Myrkl's AB001 formulation rather than as the sole branded product itself.

Other names
fermented rice branFRB
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)ACE (Angiotensin Converting Enzyme)

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