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ferric pyrophosphate + ascorbic acid
- Development stage
- Unknown
- Lead developer
- Rockwell Medical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Ferric pyrophosphate + vitamin C is a combination nutritional supplement used for the treatment and prevention of iron deficiency anemia. Ferric pyrophosphate serves as the iron source, while vitamin C (ascorbic acid) acts as an absorption enhancer by reducing ferric iron (Fe3+) to the more soluble and readily absorbed ferrous form (Fe2+) within the gastrointestinal tract. A notable formulation of this combination is sucrosomial ferric pyrophosphate, which utilizes a phospholipid bilayer (sucrosome) to encapsulate the iron, protecting it from the acidic gastric environment and reducing common side effects like metallic taste and gastrointestinal irritation. This combination is frequently used to optimize hemoglobin levels in patients with chronic kidney disease, inflammatory bowel disease, and those undergoing major orthopedic surgery.
- Brand names
- SiderALSiderAL ForteSiderAL Oro
- Other names
- ferric pyrophosphate + vitamin Csucrosomial iron + vitamin Ciron pyrophosphate + ascorbic acid
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