ferric pyrophosphate citrate + heparin

This is a **combination of ferric pyrophosphate citrate and unfractionated heparin** administered intravenously during hemodialysis. Ferric pyrophosphate citrate is an iron replacement agent designed to maintain iron balance by providing soluble iron, which is rapidly chelated by transferrin and incorporated into hemoglobin for erythropoiesis, bypassing the macrophage-mediated iron sequestration seen with traditional IV iron[1][3]. Unfractionated heparin is an anticoagulant that enhances the activity of antithrombin III, inactivates thrombin and factor Xa, and is widely used in dialysis to maintain circuit patency. Clinical studies confirm **no significant pharmacokinetic or pharmacodynamic drug-drug interactions when ferric pyrophosphate citrate is co-administered with unfractionated heparin as a single admixture, and each retains its efficacy and safety profile for iron delivery and anticoagulation**[1][2][3].

Brand names

Triferic AVNU

Other names

ferric pyrophosphate citrate and unfractionated heparin admixture