Drug intelligence / Profile preview

ferrous sulfate dihydrate

Development stage
Approved
Lead developer
Pierre Fabre
Modality
Small Molecules
Administration
Oral
01

Overview

Iron sulfate dihydrate (ferrous sulfate dihydrate) is a small molecule mineral supplement used primarily for the treatment and prevention of iron-deficiency anemia. As an oral iron salt, it provides elemental iron in the ferrous (Fe²⁺) state, which is readily absorbed in the gastrointestinal tract and utilized as a critical component of hemoglobin, myoglobin, and various heme-containing enzymes. In clinical practice, it serves as a standard oral therapy to replenish iron stores and support erythropoiesis. Recent clinical investigations, such as Phase 4 trials in Spain, have evaluated its efficacy compared to intravenous iron in reducing perioperative blood transfusions and improving hemoglobin levels in patients undergoing revascularization for chronic lower limb ischemia associated with peripheral artery disease.

Brand names
FeosolSlow FeFer-In-SolFero-Gradumet
Other names
iron sulfate dihydrateiron(II) sulfate dihydrateFeSO4·2H2O
02

Targets

SLC40A1 (Ferroportin)SLC11A2 (DMT1)

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