fetal mesencephalic dopamine neuronal precursor cells

Fetal mesencephalic dopamine neuronal precursor cells are an investigational cell therapy derived from the ventral mesencephalon of fetal tissue. These precursor cells are intended to be transplanted into the brains of patients with Parkinson's disease, specifically into the striatum. The therapeutic goal is for these cells to survive, differentiate into mature dopaminergic neurons, and integrate into the host's neural circuitry to restore dopamine levels and improve motor function. This approach aims to address the progressive loss of substantia nigra dopaminergic neurons, which is the hallmark of Parkinson's disease pathology. Clinical development, such as studies conducted at Bundang CHA Hospital, focus on evaluating the long-term safety, tolerability, and functional efficacy of these transplanted cells.

Other names

human fetal mesencephalic tissuefetal ventral mesencephalic cellshVM cellsfetal midbrain-derived dopaminergic precursor cells