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Fetal Reduction-Grande International Hospital, Nepal-multifetal pregnancy

Development stage
Unknown
Lead developer
Grande International Hospital
Modality
Small Molecules
Administration
Intracardiac
01

Overview

This refers to a specific medical procedure and clinical study conducted at Grande International Hospital in Nepal for the management of multifetal pregnancies. The intervention involves the transabdominal, ultrasound-guided intracardiac injection of potassium chloride (KCl) to reduce the number of fetuses in higher-order multiple pregnancies (e.g., triplets or quadruplets). The procedure typically uses a 15% w/v KCl solution (2 mEq/ml) in doses ranging from 0.2 to 3.0 ml, injected directly into the fetal heart to induce cardiac asystole. Performed between 7 and 15 weeks of gestation, this pioneer study in Nepal aims to improve perinatal outcomes and mitigate maternal and fetal risks associated with multifetal gestations, which are frequently a consequence of assisted reproductive technologies.

Other names
potassium chloridetransabdominal fetal reductionintracardiac potassium chloride injection

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