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Drug intelligence / Profile preview
Fexofenadine Hydrochloride Topical Lotion 1%
- Development stage
- Phase 1
- Lead developer
- OrchestratePharma GmbH
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
OP2101 (FexoTopic) is a novel, patented topical lotion formulation of fexofenadine hydrochloride, a second-generation H1-receptor selective antihistamine. Developed by OrchestratePharma GmbH, it is designed for the treatment of skin disorders characterized by pruritus, specifically mild to moderate atopic dermatitis (eczema) in both adults and children. Unlike traditional oral fexofenadine, this topical formulation aims to provide fast-acting itch relief and long-term flare-up prevention by delivering the active ingredient directly to the skin while minimizing systemic absorption. It is intended for use as a short- and long-term monotherapy.
- Brand names
- FexoTopic
- Other names
- Fexofenadine Hydrochloride Topical Lotion
02
Targets
HRH1 (Histamine H1 Receptor)KCNA3 (Potassium voltage-gated channel subfamily A member 3)PLA2G4A (Cytosolic phospholipase A2 alpha)
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