Drug intelligence / Profile preview

FhCMB HAI-05

Development stage: Phase 1
Lead developer: Fraunhofer USA Center for Molecular Biotechnology
Modality: Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration: Intramuscular

Overview

**FhCMB HAI-05** is a recombinant influenza vaccine candidate developed by the Fraunhofer USA Center for Molecular Biotechnology (FhCMB) using a plant-based transient expression system. It consists of a recombinant hemagglutinin (HA) protein, specifically designed as a poly-histidine-tagged monomer based on an H5N1 influenza strain, aimed at eliciting protective immune responses against avian influenza. Pre-clinical studies in mice, rabbits, and ferrets demonstrated its immunogenicity and safety, supporting advancement to clinical evaluation for pandemic preparedness.[2][6]

Other names: recombinant hemagglutinin A/Indonesia/05/2005 (H5N1) influenza vaccine

Targets

MHC II (Major histocompatibility complex class II receptor)

Beyond the preview

Go deeper on FhCMB HAI-05.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on FhCMB HAI-05.

Explore the full profile