fibrin glue

Fibrin glue is a biological adhesive and hemostatic agent composed of fibrinogen and thrombin, which together mimic the final stage of the natural coagulation cascade to form a stable fibrin clot. In a Phase 3 clinical trial led by Dr. Alejandro González-Ojeda at the Mexican Institute of Social Security (IMSS), this biological adhesive was evaluated for its ability to prevent surgical complications in patients undergoing living-related-donor kidney transplantation for end-stage renal disease. The study, which involved 157 recipients, demonstrated that the application of fibrin glue via a spray technique significantly reduced the incidence of postoperative complications such as lymphoceles, urinary leaks, and hematomas, thereby potentially improving graft function and reducing patient morbidity.

Brand names

TisseelArtiss

Other names

fibrin sealantfibrin adhesivebiological fibrin based adhesive