Drug intelligence / Profile preview

FibroZyme

Development stage
Unknown
Lead developer
Fibroheal Woundcare
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Topical
01

Overview

FibroZyme is a topical enzymatic debriding ointment developed by Fibroheal Woundcare Pvt. Ltd. for the management of necrotic tissue in acute and chronic wounds. The formulation contains papain, a proteolytic enzyme derived from *Carica papaya*, and urea, which serves as a denaturant to expose protein linkages, making them more susceptible to enzymatic digestion. FibroZyme is designed to selectively liquefy non-viable tissues, such as slough and necrotic debris, without harming healthy, viable tissue. It is indicated for use in various wound types, including diabetic foot ulcers, pressure ulcers, varicose ulcers, burns, and post-operative wounds, providing a non-invasive alternative to mechanical or surgical debridement.

Brand names
FibroZyme
Other names
Papain-Urea Debriding Ointment
02

Targets

Denatured/necrotic tissue proteins

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