ficus septica exudate

*Ficus septica* exudate is the latex or sap obtained from the *Ficus septica* plant (commonly known as Hauli or Septic Fig), a member of the Moraceae family native to Southeast Asia and Australia. In traditional medicine, it has been utilized for the treatment of skin diseases, wounds, and inflammatory conditions. The exudate is characterized by its high concentration of bioactive phenanthroindolizidine alkaloids, such as tylophorine, ficuseptine, and antofine. These compounds have garnered significant interest in oncology research due to their ability to inhibit protein translation and induce apoptosis in various cancer cell lines. Additionally, the exudate exhibits anti-inflammatory effects by suppressing the NF-kappaB signaling pathway and downregulating pro-inflammatory mediators such as COX-2 and various cytokines. While it is not currently an approved pharmaceutical, it remains a subject of preclinical investigation for its antineoplastic and antimicrobial potential.

Other names

ficus septica latexficus septica sapHauli sapHauli latexSeptic Fig exudate