Drug intelligence / Profile preview

FID-007C

Development stage
Discontinued
Lead developer
Fulgent Pharma
Modality
Nanoparticles → Drug Delivery Systems
Administration
Intravenous
01

Overview

FID-007C is a discontinued nanoparticle formulation of paclitaxel developed by Fulgent Pharma for the treatment of lung cancer. The drug utilizes a proprietary nanoencapsulation technology involving a polyethyloxazoline (PEOX) polymer to deliver paclitaxel, a well-established microtubule-stabilizing agent. By binding to tubulin, paclitaxel inhibits the disassembly of microtubules, which arrests the cell cycle in the G2/M phase and induces apoptosis in rapidly dividing cancer cells. While the lead candidate in this platform, FID-007, continues to be evaluated in Phase 2 trials for head and neck squamous cell carcinoma (HNSCC), the FID-007C program specifically targeting lung cancer was discontinued by the developer.

Other names
paclitaxel nanoparticle PEOX lung cancer
02

Targets

TUBB (Tubulin (alpha and beta subunits))

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