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filipendula ulmaria extract
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
*Filipendula ulmaria* extract, derived from the plant commonly known as meadowsweet, is a multicomponent herbal remedy investigated for its anti-inflammatory, antioxidant, and neuroprotective properties. The extract contains bioactive polyphenols, notably flavonoids like miquelianin (quercetin-3-O-glucuronide) and spiraeoside (quercetin-4'-O-glucoside), as well as salicylates. Research indicates its potential in modulating neuroinflammation and proteostasis, which are key drivers in neurodegenerative conditions such as Parkinson's disease. It has demonstrated geroprotective effects and the ability to enhance heat shock resistance in model organisms like *Caenorhabditis elegans*.
- Other names
- meadowsweet extractFilipendula ulmaria hydroethanolic extract
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)
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